Description
About:
Sodium starch glycolate (SSG) is a widely used pharmaceutical excipient.
It is a cross-linked sodium salt of starch and acts as a superdisintegrant.
SSG is used primarily in tablet formulations to facilitate quick disintegration.
It improves the dissolution rate of the active pharmaceutical ingredient.
The product appears as a white to off-white, odorless powder.
SSG is typically included in formulations at concentrations ranging from 2% to 10%.
Benefits:
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Enhances the disintegration of tablets in the digestive system.
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Accelerates the release of active ingredients for faster absorption.
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Improves the bioavailability of poorly soluble drugs.
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Reduces the time required for tablets to break down, leading to quicker onset of action.
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Enables the creation of tablets with controlled-release properties.
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Improves tablet consistency and stability during storage.
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Facilitates the production of tablets with lower friability.
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Provides cost-effective solutions in tablet manufacturing.
Uses:
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Tablet Formulations: Incorporated to enhance tablet disintegration and dissolution.
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Capsule Fillers: Used in capsule formulations for improved release profiles.
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Granules: Aids in the formation of granules that disintegrate quickly.
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Oral Suspensions: Assists in the suspension of powders to prevent settling.
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Chewable Tablets: Facilitates the rapid breakdown of chewable tablets.
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Effervescent Tablets: Enhances the disintegration and dissolution in effervescent formulations.
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Controlled-Release Formulations: Utilized in modified-release tablets for controlled drug delivery.
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Powder Blends: Used in powder blends to improve flowability and uniformity.
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Buccal and Sublingual Tablets: Ensures rapid disintegration for fast absorption.
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Immediate-Release Tablets: Enhances the quick release of active ingredients in immediate-release tablet formulations.